QUANTITATIVE COMPUTED TOMOGRAPHY EVALUATION OF PULMONARY DISEASE
Identifieur interne : 000A74 ( Istex/Curation ); précédent : 000A73; suivant : 000A75QUANTITATIVE COMPUTED TOMOGRAPHY EVALUATION OF PULMONARY DISEASE
Auteurs : Fintan J. Mcevoy ; Lene Buelund ; Anders B. Strathe ; Jakob L. Willesen ; J Rgen Koch ; Pia Webster [Danemark] ; Lasse H Rlyck ; Eiliv SvalastogaSource :
- Veterinary Radiology & Ultrasound [ 1058-8183 ] ; 2009-01.
English descriptors
- KwdEn :
Abstract
Objective assessment of pulmonary disease from computed tomography (CT) examinations is desirable but difficult. When such assessments can be made, it is important that they are related to some part of the pathophysiologic process present. Herein we propose that automated volume histogram analysis can yield data that allow differentiation of normal from abnormal lung, and that the magnitude of disease will have an association with objective CT indices. Data from pulmonary CT images from 34 foxes (six uninfected controls and 28 infected with Angiostrongylus vasorum, subdivided by age and infective dose) were available. Lung tissue was segmented from surrounding tissue using an automated segmentation method. A volume histogram showing voxel frequency for each CT number in the range −1024 to −250 HU was created from the entire image stack from each fox. Using these data, the inter‐quartile range and the CT number at the 95th percentile were determined. The results showed that segmentation could be readily achieved but that areas of severely diseased lung were excluded. Based on two‐way analysis of variance for both the inter‐quartile range and the CT number at the 95th percentile, both quantities were significantly affected by the infection status of the animal and were related to worm burden (P<0.001). The study shows that this form of analysis is readily achieved and provides quantitative data that can be used to assess disease severity, progression, and response to treatment.
Url:
DOI: 10.1111/j.1740-8261.2008.01488.x
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000A75
Links to Exploration step
ISTEX:580DBF0C07B47FF417AD325E75A9E1F92EE646ADCuration
No country items
Fintan J. Mcevoy<affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Department of Basic Animal and Veterinary Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark, and</mods:affiliation><wicri:noCountry code="subField">and</wicri:noCountry></affiliation><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation>Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">QUANTITATIVE COMPUTED TOMOGRAPHY EVALUATION OF PULMONARY DISEASE</title><author><name sortKey="Mcevoy, Fintan J" sort="Mcevoy, Fintan J" uniqKey="Mcevoy F" first="Fintan J." last="Mcevoy">Fintan J. Mcevoy</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Buelund, Lene" sort="Buelund, Lene" uniqKey="Buelund L" first="Lene" last="Buelund">Lene Buelund</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Strathe, Anders B" sort="Strathe, Anders B" uniqKey="Strathe A" first="Anders B." last="Strathe">Anders B. Strathe</name><affiliation><mods:affiliation>Department of Basic Animal and Veterinary Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark, and</mods:affiliation><wicri:noCountry code="subField">and</wicri:noCountry></affiliation></author><author><name sortKey="Willesen, Jakob L" sort="Willesen, Jakob L" uniqKey="Willesen J" first="Jakob L." last="Willesen">Jakob L. Willesen</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Koch, J Rgen" sort="Koch, J Rgen" uniqKey="Koch J" first="J Rgen" last="Koch">J Rgen Koch</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Webster, Pia" sort="Webster, Pia" uniqKey="Webster P" first="Pia" last="Webster">Pia Webster</name><affiliation wicri:level="1"><mods:affiliation>Danish Centre of Experimental Parasitology, Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Centre of Experimental Parasitology, Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="H Rlyck, Lasse" sort="H Rlyck, Lasse" uniqKey="H Rlyck L" first="Lasse" last="H Rlyck">Lasse H Rlyck</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Svalastoga, Eiliv" sort="Svalastoga, Eiliv" uniqKey="Svalastoga E" first="Eiliv" last="Svalastoga">Eiliv Svalastoga</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:580DBF0C07B47FF417AD325E75A9E1F92EE646AD</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1111/j.1740-8261.2008.01488.x</idno><idno type="url">https://api.istex.fr/document/580DBF0C07B47FF417AD325E75A9E1F92EE646AD/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000A75</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000A75</idno><idno type="wicri:Area/Istex/Curation">000A74</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">QUANTITATIVE COMPUTED TOMOGRAPHY EVALUATION OF PULMONARY DISEASE</title><author><name sortKey="Mcevoy, Fintan J" sort="Mcevoy, Fintan J" uniqKey="Mcevoy F" first="Fintan J." last="Mcevoy">Fintan J. Mcevoy</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Buelund, Lene" sort="Buelund, Lene" uniqKey="Buelund L" first="Lene" last="Buelund">Lene Buelund</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Strathe, Anders B" sort="Strathe, Anders B" uniqKey="Strathe A" first="Anders B." last="Strathe">Anders B. Strathe</name><affiliation><mods:affiliation>Department of Basic Animal and Veterinary Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark, and</mods:affiliation><wicri:noCountry code="subField">and</wicri:noCountry></affiliation></author><author><name sortKey="Willesen, Jakob L" sort="Willesen, Jakob L" uniqKey="Willesen J" first="Jakob L." last="Willesen">Jakob L. Willesen</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Koch, J Rgen" sort="Koch, J Rgen" uniqKey="Koch J" first="J Rgen" last="Koch">J Rgen Koch</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Webster, Pia" sort="Webster, Pia" uniqKey="Webster P" first="Pia" last="Webster">Pia Webster</name><affiliation wicri:level="1"><mods:affiliation>Danish Centre of Experimental Parasitology, Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Denmark</mods:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Centre of Experimental Parasitology, Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen</wicri:regionArea></affiliation></author><author><name sortKey="H Rlyck, Lasse" sort="H Rlyck, Lasse" uniqKey="H Rlyck L" first="Lasse" last="H Rlyck">Lasse H Rlyck</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author><author><name sortKey="Svalastoga, Eiliv" sort="Svalastoga, Eiliv" uniqKey="Svalastoga E" first="Eiliv" last="Svalastoga">Eiliv Svalastoga</name><affiliation><mods:affiliation>Department of Small Animal Clinical Sciences, Faculty of Life Sciences, University of Copenhagen, Denmark,</mods:affiliation><wicri:noCountry code="subField"></wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Veterinary Radiology & Ultrasound</title><idno type="ISSN">1058-8183</idno><idno type="eISSN">1740-8261</idno><imprint><publisher>Blackwell Publishing Inc</publisher><pubPlace>Malden, USA</pubPlace><date type="published" when="2009-01">2009-01</date><biblScope unit="volume">50</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="47">47</biblScope><biblScope unit="page" to="51">51</biblScope></imprint><idno type="ISSN">1058-8183</idno></series><idno type="istex">580DBF0C07B47FF417AD325E75A9E1F92EE646AD</idno><idno type="DOI">10.1111/j.1740-8261.2008.01488.x</idno><idno type="ArticleID">VRU01488</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1058-8183</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Angiostrongylus vasorum</term><term>CT</term><term>histogram analysis</term><term>lung</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Objective assessment of pulmonary disease from computed tomography (CT) examinations is desirable but difficult. When such assessments can be made, it is important that they are related to some part of the pathophysiologic process present. Herein we propose that automated volume histogram analysis can yield data that allow differentiation of normal from abnormal lung, and that the magnitude of disease will have an association with objective CT indices. Data from pulmonary CT images from 34 foxes (six uninfected controls and 28 infected with Angiostrongylus vasorum, subdivided by age and infective dose) were available. Lung tissue was segmented from surrounding tissue using an automated segmentation method. A volume histogram showing voxel frequency for each CT number in the range −1024 to −250 HU was created from the entire image stack from each fox. Using these data, the inter‐quartile range and the CT number at the 95th percentile were determined. The results showed that segmentation could be readily achieved but that areas of severely diseased lung were excluded. Based on two‐way analysis of variance for both the inter‐quartile range and the CT number at the 95th percentile, both quantities were significantly affected by the infection status of the animal and were related to worm burden (P<0.001). The study shows that this form of analysis is readily achieved and provides quantitative data that can be used to assess disease severity, progression, and response to treatment.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/RenardV1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A74 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000A74 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Bois
|area= RenardV1
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:580DBF0C07B47FF417AD325E75A9E1F92EE646AD
|texte= QUANTITATIVE COMPUTED TOMOGRAPHY EVALUATION OF PULMONARY DISEASE
}}
| This area was generated with Dilib version V0.6.27. |  |